The players have a chance to cure the plague that has sprouted up upon their travels. Will they choose to do the right thing and help bring health back to the region?
Hidden above an alcove behind a forgotten waterfall could be one of the last intact temples of a long persecuted religious order dedicated to the worship of their water elemental patron.
To be used for the final encounter, find the final treasure, or anything that needs to be hidden away better then normal. Typical “who the heck would ever spend the time making it” but it is fun and a mental challenge for a change.
At regular intervals, a god takes control of your world's weather. Choose the gods at random each turn of the interval and begin applying their effects subtly. Their power will depend on the strength of those who worship them.
For civilised people, worship of a god actually wanes during that god's month in an effort to reduce their potential destructive effect.