A group of adventurers come across a child’s body on their adventures, odd being such a remote location. Their is no detectable sign of violence to the child, nor are their any signs of life. Suddenly the child opens its eyes, looks towards the group and introduces themselves to the adventures.
If this wasn’t odd enough, the child can’t remember where they are from, only their name and age. Stranger yet, the child has a tattoo on their right shoulder of a family crest, to a family that died out over 200 years ago.
The local band of 'nasties' (goblins / orcs / whatever) lives in relative peace with the local population.
Along come the PCs and go through their usual heroic monster bashing routine, wiping out the nasties and pinching all their stuff, then continue on their way.
Problem is, they don't kill ALL he nasties. The survivors want revenge and, after spending a few months recovering, start to take it in their own inimitable style (which is not unlike that of the PCs come to think of it).
Next time the PCs are in the area they find themselves VERY unpopular with the townsfolk.