You receive a vision of a rooftop "somewhere close by", where a rare moss grows; in the vision, you know the moss is suitable for greatly enhancing the effects of certain types of potions. Now go and find that rooftop. Don't fall off. (Of course, rooftop runners *will* be taken for miscreants by the local City Watch....)
The members of the party has unknowingly been infected by a mysterious plague and have been spreading the virus for quite some time now while adventuring. They start to hear rumors of all the cities in quarantine after they travelled trough. Will they discover the source of this? Will people start to avoid them, try to kill them?