Actually a real-world fungus, just heard about it. A fungus that tastes well and all, no ill effects. UNLESS you consume some beverage, even 3 (three) days after eating it. Then you become really sick, pains, vomiting, all the fancy stuff. Was really used to cure alcoholism. May be a joke or to make sure the heroes spend their time focused on the mission.
Plant that is likely to produce allergic reactions in almost everybody, even by touch. Usage: medicinal, in very exotic foods, non-lethal traps, disabling opponents (have you ever cut an onion,anyway?), spell components, etc.
A local fungus-breed explodes if hit or fallen upon. If there is any conflict between inteligent enemies,both sides are likely to use it to their advantage.
The PCs have been traveling for a long time down the same stretch or round with no sign of anything suspicious. As they cross over to the next hill they see a gigantic splater of blood with a bleached dragons scull in the center of it. It the dragon skull's mouth is a tattered backpack with something wiggling inside of it.