The characters are given the task of transporting a flask of highly volatile liquid a long distance. The flask cannot be shaken too much or it will explode. The adventure involves stormy sea-voyages, bumpy cart rides through densely populated towns and horseback combat. In short there are many opportunities for it to break and explode.
Minor Cultural Modifier: The culture believes, for the soul to leave the body, the corpse' eyes must be open. So any member of that culture takes care any dead body they find has its eyes open. Doubly true for those they kill themselves, for then the corpse will surely rise as an undead hunting him.