All spell casters gain their abilities through a form of demon possession. So in order to gain magical abilites, PCs must track down and trap demons. Of course there are some pretty powerful demons, if the demon is stronger than the PC, the PC could find themselves subjugated to the Demon's will.
In an area albinos are considered to be evil mystics and locals ward themselves against them by turning their backs to them to avoid being mesmerized. Suddenly the angeliclly pale loner with white hair and violet hued-eyes is suddenly an outcast, and his companions are treated as if they have been mystically bonded into his service, and could be treated with attempts to intervene or given the same stony treatment. Expect poor quarters, no hospitality and to pay twice as much for everything.