All spell casters gain their abilities through a form of demon possession. So in order to gain magical abilites, PCs must track down and trap demons. Of course there are some pretty powerful demons, if the demon is stronger than the PC, the PC could find themselves subjugated to the Demon's will.
A secret MLM (pyramid) company that offers eternal life, but in fact it transfers the life forces of its members to those position "above". If you get high enough, (meaning you get enough new members) you start to enjoy the benefits. Maybe a willing sacrifice is much more effective for the transfer. But no one says, that a suddenly unwilling member, threatening to tell the authorities, may not loose it involuntarily... thus start people to vanish, and aged corpses are deposited somewhere safe.