I once read a book about a group of people who discovered a hidden temple city in a mountain range, where the Incas-the ancient civilisation of Peru- had fled to when the spanish invaded. When this group found the burial chamber of one of the inca high priests, they unleashed a powerful curse upon them all...
The members of the party has unknowingly been infected by a mysterious plague and have been spreading the virus for quite some time now while adventuring. They start to hear rumors of all the cities in quarantine after they travelled trough. Will they discover the source of this? Will people start to avoid them, try to kill them?