A typical iron ore mine, the Irongate was closed some years ago and the entrance was closed off with a heavy gate of oak and thick iron bands, the Irongate. The mine itself was abandoned because it was a breeding ground for dire rats and many of the miners suffered from giant rodent bites as well as diseases from said bites. The mines are haunted by the ghosts of the men who died in dire rat swarms, adding to the mine's unpleasant character.
When was the last time a character caught a cold or flu? Real people get them every now and again even with solid heating and dry interiors. Your characters are out in the cold and wet, and even inside is not always dry and warm. Imagine having to stop your dungeon crawl, sitting in a tight defensive position, while you all are feverish.