If a creature is transformed into another creature (say, a human into a dog), then that creature will become more and more accustomed to the new form until a point is reached where reversing the spell is impossible. A second transformation is possible, but the creature will have to go through the whole process again.
An ancient, psuedo-immortal race has been manipulating something important (politics, religion, economics, etc.) for centuries. Hardly anyone is aware of them, let alone their goals.
Beware of towns afflicted with Time Cancer.
For every second you progress through time, an infected town goes back 48 hours. Old buildings slowly become new, then incomplete, and finally just a frame and foundation, giant old trees turn to saplings, birds hatch into eggs.
one must not linger in a chrono-cancerous village for too long, before you know it you'll be a fetus. Tme cancer in unstoppable, no cure or treatment is knwn, it eats through the past until the inhabitants of a village turn into primordial protein ooze