The nations of the Kolm surpasses all other barbarians in their wilderness of life. Thoug they do just bear the likeness of men, of a very ugly pattern, they are so little advanced in civilization that they make no use of fire, nor any kind of relish, in the preparation of their food, but feed upon the roots which they find in the fields, and the half-raw flesh of any sort of animal. I say half-raw, because they give it a kind of cooking by placing it between their own thighs and the back of their horses. They fight in no regular order of battle but by being extremely swift and sudden in their movements, they disperse, and hen rapidly come toghether in loose array. They spread havoc over the vast plains and flying over the ramparts, they pillage the camp of their enemy almost before he has become aware of their approach. They are the most terrible warriors for when in close combat with swords and flails they fight without regard to their own safety, and while their enemy is intent upon parrying the thrust of the swords, they will entangle him with their chains so that he loses all power of walking or riding.
Excerpt from "The peoples of the world" By Taklamarian court-scholar Guliman Amon.
Pick up a pathology/microbiology book, and add the diseases/syndroms to your game. Your players will freak out.
Coughed at? Diphteria. or tuberculosis?
Drunk from a muddy stream? Or just walked through? Well, let us introduce you to schistosomiasis...
Hit by a stream of energy? Too moch mana is ust like too much radioactivity - perhaps all mages could develop cancer early if too powerful...