A long time ago. Final fantasy III came out with a new approach to learing magic. The characters would be equipped with espers(magical beings) and as they fought more battles, they would learn spells from the espers. What if a similar approach to learning magic was applied to a P&P rpg?
An alchemist enchanted his equipment to produce even more powerful alchemical compounds, potions and the like. Unfortunately, it is not well-known that he had different sets of equipment for different processes: If the wrong set of gear is used, the result will invariably fail to function. It's not a cursed item, just something that's hard to figure out.