In a small inn (the more remote the better), a man turns up dead. There are no wounds on his body what-so-ever, and he aboslutely reeks of garlic.
The man died of a curse that forced him to eat a clove of garlic a day or suffer the penalty. This gets really interesting if the body somehow appears on top of a someone the villagers are suspcious of.
The local band of 'nasties' (goblins / orcs / whatever) lives in relative peace with the local population.
Along come the PCs and go through their usual heroic monster bashing routine, wiping out the nasties and pinching all their stuff, then continue on their way.
Problem is, they don't kill ALL he nasties. The survivors want revenge and, after spending a few months recovering, start to take it in their own inimitable style (which is not unlike that of the PCs come to think of it).
Next time the PCs are in the area they find themselves VERY unpopular with the townsfolk.