Animals have parasites and diseases, so do plants, there are even bacteria that cann dissolve oil spills or plastic or what have you - why couldn't there be a disease living off magic - a magic item could be infected, losing power and speading the plague to other equipment it contacts, while a magic user would slowly lose his powers and contaminate all he works with or casts a spell at...
"Binding the Life Coil" is an ancient quasi-mystical technique rediscovered to prolong one's life at the expense of one reproductive ability. It is a simple magikal technique that anyone can learn (a skill or feat). The promise of near immortality or a lifespan of a thousand years or more makes everyone want to learn it.
This technique has a price though, the amount of immortality is in direct response to the strength of ones reproductive spirit. Those that have never breed will live longer than those that have. The use of the technique makes conception difficult, if not impossible. So you trade the future of your society for the chance for you to see much of that future.