An orc male who dislikes the hard warrior life, has disguised himself as an orc female and is learning how to become a Shaman. If uncovered as a male, his fellow orcs will be disgusted enough to kill him.
A group of wizards who will give others temporary magical powers, but the price is high and those who can't pay or won't pay get very badly hurt or even killed.
Next time you're contemplating a horse variation, but don't want to get too dramatic, how about a Zorse? An offspring of a zebra stallion and horse mare. In nature they are infertile, but in a fantasy world, not necessarily. They are also known to be extremely cantankerous.
"It soon became apparent that zorses are not the most easiest of the equine family to get along with." -- Trainer Pat Parelli, on working with zorses