The limb that got away and became the symbol of a revolution.
Maxilan Carth, the Hunter of the Bayous, was the bane of the gatorfolk in life. To those who follow Jampiri, he provides protection from those beasts from beyond the grave.
The teeth and fingerbones of holy men and more
The Road to the Hundred Angels
The PCs are walking along the road, when suddenly a bunch of bandits attacks. The player's dismiss it has just a random encounter, when they find an ornate ring on the leader, obviously out of place with the seemingly poor bandits, who could only afford cheap leather and weapons. This ring has a symbol on it, which, if researched, sets the PCs on a quest. And from then on, the players don't look at random encounters the same way...