They say you give up a few things, chasing a dream. In those mists that's the literal truth, for every dream of yours that comes true, a piece of yourself, mind, body, or soul, gets taken by the mist. Worst part is, you won't even know what the cost of your dreams are until you go to leave, and by then you might not even have a mind left to change...
A fragment of the mists of creation, drawn to those desperate to make their dreams come true. Suitable for any magical fantasy setting.
A village where everyone goes blind sometime during puberty. What could be causing this? Perhaps something in their diet. Or some malignant gene. How would an entire village where only young childen can see function?