Elephants crossing the seas!
It is not an infectious disease, but it is a plague upon the world.
For it spawns villains. And not your garden variety villains, but epic villains, master villains of the most dangerous kind Evil Geniuses.
Pnathic sorcery has existed for ages, crudely used by magi who no idea the true forces they were fumbling with.
An article concerning the nature and role of druids in an RPG enviroment.
Plagues and other great diseases are important parts of history and some settings. They defy man and may even defy God in their swift and terrible punishment upon the body of society.
The size and number of knots in hair, tied around neck, or hanging from belt could signify family, importance, worship, guild affiliations. Being able to translate the meaning of the size and placement of knots can give you a a large understanding of who somebody is.
May be used in a more barbaric society. Where in cities peoples clothes and crests show who they are, barbarians have no need for this so use knots.