A dangerous, alien plane where glowing frog-slimes slither and slurp, metal-skinned bird people rebuff diplomacy, and only the endless subterranean tunnels are safe (just mind the gravity-bending moles). Visitors will have to skulk around in the dark to avoid the curse carried by the sunlight. Because (have I mentioned?) the sun is the source of a powerful curse--one that covers the whole planet.
Imagine a tribe of nomads where all the males have the blessing of being were-stallions. The tribe would not need to have ordinary horses to move around, all mounted warriors would be female and a curious custom could be that when a couple gets married, the girl rides her chosen to the altar.