In a world where teleportation magic doesn’t exist, the opportunity to travel a few days journey in moments is beyond value. With only a simple toll, you can be practically on the doorstep of Nizul-tibi before you know it.
Consider the idea of spontaneous genesis of life, as used to be belived. What strange kinds of life might arise from modern substances? What kind of vermin would a landfill produce, or an oil spill on the ocean?