Elephants crossing the seas!
It is not an infectious disease, but it is a plague upon the world.
For it spawns villains. And not your garden variety villains, but epic villains, master villains of the most dangerous kind Evil Geniuses.
Pnathic sorcery has existed for ages, crudely used by magi who no idea the true forces they were fumbling with.
An article concerning the nature and role of druids in an RPG enviroment.
Of creatures great and small
The Omen Plague has other names. It is known as The Star Plague and even The Mundane Plague. It is still with us today, now known by the common name of the Shaking Death. To set the stage, the stars were aligned in all the wrong signs. Everyone new something bad was going to happen. When winter set in hard and early, they thought that was it. They were wrong.
Plagues and other great diseases are important parts of history and some settings. They defy man and may even defy God in their swift and terrible punishment upon the body of society.
Trying to find a place for this...
"After the famine hit the land, the priest Galen began religious wanderings, drawing his congregation to follow him. Those who took up with him, began to walk, a great outpouring of energy to this religious pilgrimage, coming from an impoverished nation with no true direction other than to find relief. Galen professed to his followers that they would find great resources set by his God down on Earth for them, enough to nourish and slate their thirst. Those that fell as he took them across the barren plains of the western reaches, rose again to join the lines. When finally all had died, Galen led them further, praising Nuh-Erell for that first city they came upon and a feast of flesh that lay in wait"