A dangerous, alien plane where glowing frog-slimes slither and slurp, metal-skinned bird people rebuff diplomacy, and only the endless subterranean tunnels are safe (just mind the gravity-bending moles). Visitors will have to skulk around in the dark to avoid the curse carried by the sunlight. Because (have I mentioned?) the sun is the source of a powerful curse--one that covers the whole planet.
God has been slayed by a mortal man and his head is now worshipped and put on a pedestal. The PCs are hired to steal the head and bring it to a mystic that claims to have the power to revive God.