Classified as a category 4 threat, the Elib is somewhere between a vampire lord and Godzilla for limits of escalation. Yes, I would consider using a nuclear device to kill just one. I am that sure that I want it dead.
The Mad Pope is a wandering mercenary. He is very well deranged as he considers himself to be the pontiff of the dominant faith. His robes are tattered, his mitre has seen better days and there are surely lice in his long ratty beard. What sets him apart from most addle-pated would be holy men is that he has armor under his robes and carries a large crossbow and several one-handed swords. While many would discout him as just another lunatic, for some reason, he inspires others around him and has demonstrated the ability to lay on hands and heal the wounded.