I like the combining of genres and settings to produce something new. They had spies in the Renaissance times, each prince/ household against the others. I could see a campaign of spy vs spy set in Italy in the late 1300s. Go to Comment
I don't think it would skyrocket, as after a while people would realize that nobody comes back. I would think it was quarentined.
Very cool if the PCs were inside the city, solved the problem, then had to deal with the repercussions to their lives being gone for a couple of years - especially if they were important or on an important mission when they were passing through. Go to Comment
In a small, genetically isolated region it is not uncommon for the locals to have three arms. The third arm is generally a second right arm that is a good bit weaker than a normal arm and is generally held against the chest. This hird arm is most often used to carry small things, though some of the more skilled craftsmen have learned little tricks with their third arm.