Deeping Steppes as named by Dargain the Gnomish adventurer who happened upon this place when attempting to find lost friends in a nearby series of caves and was swept in by the unexpected surge of an underground river, perhaps due to shifting of plates or erosion of a natural barrier. The cavern was sealed and unknown until being discovered by Dargain.
This is a region of the underdark where a series of very large plateaus occupy a huge underground cavern. The cavern is situated near a very common and sometimes treacherous underdark route know as The Underway (in my version of the world) which reaches from the Dales to Silverymoon regions in the Forgotten Realms.
God has been slayed by a mortal man and his head is now worshipped and put on a pedestal. The PCs are hired to steal the head and bring it to a mystic that claims to have the power to revive God.