Deeping Steppes as named by Dargain the Gnomish adventurer who happened upon this place when attempting to find lost friends in a nearby series of caves and was swept in by the unexpected surge of an underground river, perhaps due to shifting of plates or erosion of a natural barrier. The cavern was sealed and unknown until being discovered by Dargain.
This is a region of the underdark where a series of very large plateaus occupy a huge underground cavern. The cavern is situated near a very common and sometimes treacherous underdark route know as The Underway (in my version of the world) which reaches from the Dales to Silverymoon regions in the Forgotten Realms.
The local band of 'nasties' (goblins / orcs / whatever) lives in relative peace with the local population.
Along come the PCs and go through their usual heroic monster bashing routine, wiping out the nasties and pinching all their stuff, then continue on their way.
Problem is, they don't kill ALL he nasties. The survivors want revenge and, after spending a few months recovering, start to take it in their own inimitable style (which is not unlike that of the PCs come to think of it).
Next time the PCs are in the area they find themselves VERY unpopular with the townsfolk.