"What you wanna go messin' around up in the mountains for? Ain't nothin' up there but snow, and wolves, and more snow.
Yer lookin' for the old tomb? Take my advice, boys. Let that tomb alone. There ain't nothin up there you ought be messin' with. No money, no treasure, no fame, just ice. And death."
If a creature is transformed into another creature (say, a human into a dog), then that creature will become more and more accustomed to the new form until a point is reached where reversing the spell is impossible. A second transformation is possible, but the creature will have to go through the whole process again.