An item that puts a horible curse on the victims of its spell.
A dark emperors gloves that make an excelent weapon and torture tool.
Elementalist have commonly used jems to further their powers over nature.
Consider the idea of spontaneous genesis of life, as used to be belived. What strange kinds of life might arise from modern substances? What kind of vermin would a landfill produce, or an oil spill on the ocean?