A land being plunged into chaotic energies, wild superstition, massive prejudices and distrust. More of a campaign setting than anything else.
This is more of a concept applied to a particular setting than the setting itself, bear this in mind.
Magical curses are rarely cast, as if cast on someone for fun or purely maliciously and the person cursed has not done something seriously wrong, it tends to ricochet back on the curser. Therefore the few who do get cursed are shunned by most people as genuinely guilty,and few will help them.