Curse those greedy delvers! But what with? I know! How about Aurophobia, fear of gold? Or Barophobia, fear of gravity? And I can hit that annoying wizard with Bibliophobia, no more spells for him!
The TRUE origins of Magic, and dont even get me started on Prophecy.
An alchemist enchanted his equipment to produce even more powerful alchemical compounds, potions and the like. Unfortunately, it is not well-known that he had different sets of equipment for different processes: If the wrong set of gear is used, the result will invariably fail to function. It's not a cursed item, just something that's hard to figure out.