The followers of the mechanogod Whrrrm, those who could never have come about until the advent of steamtech.
And because they had shown they could not be trusted, Iev abolished the use of Kren save by those few individuals he trusted.
~The True History of the Order, by F’ian circa 300 AW
An alchemist enchanted his equipment to produce even more powerful alchemical compounds, potions and the like. Unfortunately, it is not well-known that he had different sets of equipment for different processes: If the wrong set of gear is used, the result will invariably fail to function. It's not a cursed item, just something that's hard to figure out.